Across TCGA pan-cancer cohorts, NANOGNBP1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of NANOGNBP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where NANOGNBP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NANOGNBP1 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

LUSC and KIRP are the cancer types where NANOGNBP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NANOGNBP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	II,III,IV	+0.033	.038	2	view →
KIRP	All	All	−0.026	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: NANOGNBP1 RNA expression & survival · all NANOGNBP1 data types