Across TCGA patient cohorts, NANOGNB mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NANOGNB-associated genes across cancer lineages are MIR7702, RNA5SP24, and MIR4778. Each is linked with NANOGNB in more than 1 cancer types. Because this analysis shows association rather than direction, both NANOGNB-to-partner and partner-to-NANOGNB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NANOGNB→partner) and Y-score (partner→NANOGNB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7702 →	+0.469	+5.475	<.001	.001	3	1
BRCA	RNA5SP24 →	+0.337	+7.731	<.001	.009	3	1
BRCA	MIR4778 →	+0.390	+8.471	<.001	.005	3	1
BRCA	SNORD115-3 →	+0.380	+7.731	<.001	.009	3	1
BRCA	RNA5SP27 →	+0.282	+7.731	<.001	.009	3	1
BRCA	RNU6-555P →	+0.314	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

NANOGNB survival (RNA) · tumor vs normal (RNA) · all NANOGNB data types