NAMPT

Across TCGA patient cohorts, NAMPT protein abundance is significantly associated with the RNA expression of many other genes, with 18,656 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NAMPT-associated genes across cancer lineages are NAMPTP1, SOD2, and CXCL8. Each is linked with NAMPT in more than 9 cancer types. Because this analysis shows association rather than direction, both NAMPT-to-partner and partner-to-NAMPT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAMPT versus NAMPTP1 in GBM, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAMPT→partner) and Y-score (partner→NAMPT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NAMPTP1 →	+1.388	+0.959	<.001	<.001	3	10
GBM	SOD2 →	+1.594	+0.939	<.001	<.001	3	7
UCEC	CXCL8 →	+1.972	+0.466	<.001	<.001	3	7
BRCA	CEBPB →	+0.838	+0.452	<.001	<.001	3	7
UCEC	LUCAT1 →	+1.067	+0.539	<.001	<.001	3	7
UCEC	SPP1 →	+1.914	+0.495	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,656 associations by consensus.

NAMPT vs NAMPTP1 — GBM

Explore this scatter interactively →