NAMPT

Across TCGA cell cohorts, NAMPT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,663 significant associations in total. CNS shows the largest number of these associations.

The most reproducible NAMPT-associated GO terms across cancer lineages are Intestinal lipid absorption, Positive regulation of protein exit from endoplasmic reticulum, and Nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway. Each is linked with NAMPT in more than 11 cancer types. Because this analysis shows association rather than direction, both NAMPT-to-partner and partner-to-NAMPT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intestinal lipid absorption grouped by NAMPT-low versus NAMPT-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAMPT→partner) and Y-score (partner→NAMPT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Intestinal lipid absorption →	+0.275	+1.440	<.001	<.001	2	12
BONE	Positive regulation of protein exit from endoplasmic reticulum →	+0.094	+0.822	.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway →	+0.098	+1.170	<.001	<.001	3	10
BONE	Regulation of ER to Golgi vesicle-mediated transport →	+0.094	+0.978	.004	.001	3	10
SOFT_TISSUE	Viral process →	+0.073	+1.004	<.001	.006	3	10
BONE	Elastin metabolic process →	+0.253	+0.872	<.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,663 associations by consensus.

Intestinal lipid absorption by NAMPT expression — SOFT_TISSUE

Explore this box plot interactively →