NAMA

Across TCGA pan-cancer cohorts, NAMA RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated NAMA data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher NAMA RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NAMA expression acts as an unfavorable survival marker, although some lineages such as READ and KIRP show a favorable association.

UVM, ACC, and READ are the cancer types where NAMA RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	III,IV	0.219	0.923	<.001	110	view →
ACC	DFS	Median	All	0.220	0.624	<.001	77	view →
READ	OS	Median	II,III,IV	0.892	0.433	<.001	68	view →
KIRP	OS	Median	All	0.932	0.581	.004	57	view →
HNSC	OS	Quartile	III,IV	0.612	0.305	.003	43	view →
PAAD	DFS	Median	All	0.441	0.274	.003	37	view →
SKCM	DFS	Tertile	All	0.806	0.682	.001	26	view →
UCS	OS	Tertile	II,III,IV	0.805	0.398	.007	26	view →
THCA	OS	Median	II,III,IV	0.958	0.993	.003	26	view →
GBM	DFS	Quartile	All	0.570	0.239	.002	10	view →
PRAD	DFS	Quartile	All	0.790	0.933	<.001	10	view →
BLCA	OS	Tertile	IV	0.153	0.396	.018	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

NAMA–UVM (DFS)

Open the UVM breakdown →