NAGS

Across TCGA patient cohorts, NAGS protein abundance is significantly associated with the RNA expression of many other genes, with 236 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible NAGS-associated genes across cancer lineages are TEX37, IGKV1OR2-3, and MIR1271. Each is linked with NAGS in more than 1 cancer types. Because this analysis shows association rather than direction, both NAGS-to-partner and partner-to-NAGS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAGS versus TEX37 in LUAD, with a Pearson correlation of -0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAGS→partner) and Y-score (partner→NAGS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TEX37 →	-0.133	-1.319	<.001	.007	3	1
LUAD	IGKV1OR2-3 →	-0.350	-1.319	<.001	.007	3	1
LUAD	MIR1271 →	-1.116	-1.389	.001	.009	3	1
LUAD	HMGB3P20 →	-0.336	-1.319	<.001	.007	3	1
LUAD	NT5DC1P1 →	-0.076	-1.391	<.001	.008	3	1
LUAD	NLRP9P1 →	-0.070	-1.319	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 236 associations by consensus.

NAGS vs TEX37 — LUAD

Explore this scatter interactively →