Across TCGA patient cohorts, NAGLU RNA expression is significantly associated with the go_rna of many other GO terms, with 7,164 significant associations in total. OV shows the largest number of these associations.

The most reproducible NAGLU-associated GO terms across cancer lineages are Sequestering of iron ion, Positive regulation of RNA export from nucleus, and Regulation of snRNA transcription by RNA polymerase II. Each is linked with NAGLU in more than 22 cancer types. Because this analysis shows association rather than direction, both NAGLU-to-partner and partner-to-NAGLU results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAGLU→partner) and Y-score (partner→NAGLU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Sequestering of iron ion →	+0.105	+0.699	<.001	<.001	3	23
STAD	Positive regulation of RNA export from nucleus →	-0.040	-0.282	<.001	<.001	3	19
DLBC	Regulation of snRNA transcription by RNA polymerase II →	-0.043	-0.403	.002	<.001	2	18
THYM	Negative regulation of RIG-I signaling pathway →	+0.052	+0.915	<.001	<.001	3	16
LAML	Sulfur compound transport →	+0.036	+0.557	<.001	<.001	3	16
TGCT	Protein import into peroxisome matrix, substrate release →	+0.047	+0.554	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,164 associations by consensus.

Exploration

NAGLU survival (RNA) · tumor vs normal (RNA) · all NAGLU data types