NAGLU

Across TCGA cell cohorts, NAGLU RNA expression is significantly associated with the go_rna of many other GO terms, with 4,255 significant associations in total. CNS shows the largest number of these associations.

The most reproducible NAGLU-associated GO terms across cancer lineages are Heparan sulfate proteoglycan catabolic process, Proteoglycan catabolic process, and Negative regulation of respiratory burst involved in inflammatory response. Each is linked with NAGLU in more than 15 cancer types. Because this analysis shows association rather than direction, both NAGLU-to-partner and partner-to-NAGLU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heparan sulfate proteoglycan catabolic process grouped by NAGLU-low versus NAGLU-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAGLU→partner) and Y-score (partner→NAGLU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Heparan sulfate proteoglycan catabolic process →	+0.228	+0.858	<.001	<.001	3	16
BONE	Proteoglycan catabolic process →	+0.186	+0.875	<.001	<.001	3	16
BLOOD_Lymphoma	Negative regulation of respiratory burst involved in inflammatory response →	+0.134	+0.897	<.001	<.001	3	14
BLOOD_Lymphoma	Negative regulation of respiratory burst →	+0.134	+0.897	<.001	<.001	3	14
BREAST	Retrograde transport, endosome to Golgi →	+0.069	+0.865	.002	.004	3	14
SKIN	Cytosolic transport →	+0.075	+0.968	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,255 associations by consensus.

Heparan sulfate proteoglycan catabolic process by NAGLU expression — BONE

Explore this box plot interactively →