Across TCGA pan-cancer cohorts, NAGA mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NAGA data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NAGA mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NAGA expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

UCEC, LSCC, and LUAD are the cancer types where NAGA mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	0.274	1.000	.001	28	view →
LSCC	OS	Median	III,IV	0.527	0.895	.011	17	view →
LUAD	OS	Tertile	II,III,IV	0.879	0.321	.006	8	view →
HNSC	OS	Median	IV	0.565	0.815	.013	7	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: NAGA tumor-vs-normal RNA expression · all NAGA data types