Across TCGA cell cohorts, NAGA mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NAGA-associated genes across cancer lineages are IL17F, CHST9, and GOLGA6C. Each is linked with NAGA in more than 1 cancer types. Because this analysis shows association rather than direction, both NAGA-to-partner and partner-to-NAGA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAGA→partner) and Y-score (partner→NAGA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IL17F →	+0.051	+3.855	<.001	.007	3	1
BLOOD_Leukemia	CHST9 →	+0.017	+4.387	.008	.001	3	1
BLOOD_Leukemia	GOLGA6C →	+0.074	+3.934	<.001	.005	3	1
BLOOD_Leukemia	SFT2D3 →	+0.569	+4.450	<.001	.001	3	1
BLOOD_Leukemia	TPRX1 →	+0.010	+4.060	<.001	.003	3	1
BLOOD_Leukemia	PRR30 →	+0.010	+4.269	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

NAGA survival (RNA) · tumor vs normal (RNA) · all NAGA data types