NAF1

Across TCGA cell cohorts, NAF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,415 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NAF1-associated GO terms across cancer lineages are Pseudouridine synthesis, RNA 3'-end processing, and rRNA pseudouridine synthesis. Each is linked with NAF1 in more than 16 cancer types. Because this analysis shows association rather than direction, both NAF1-to-partner and partner-to-NAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pseudouridine synthesis grouped by NAF1-low versus NAF1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAF1→partner) and Y-score (partner→NAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Pseudouridine synthesis →	+0.110	+0.776	<.001	.004	3	17
BONE	RNA 3'-end processing →	+0.084	+0.756	<.001	.001	3	16
BONE	rRNA pseudouridine synthesis →	+0.114	+0.837	<.001	<.001	3	16
SOFT_TISSUE	Spindle assembly →	+0.074	+0.792	.002	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.180	+0.893	.001	<.001	3	15
BONE	Ribosome biogenesis →	+0.110	+0.847	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,415 associations by consensus.

Pseudouridine synthesis by NAF1 expression — LIVER

Explore this box plot interactively →