NADSYN1

Across TCGA patient cohorts, NADSYN1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,391 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NADSYN1-associated genes across cancer lineages are DHCR7, ATP6V0E1, and KLF12. Each is linked with NADSYN1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NADSYN1-to-partner and partner-to-NADSYN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NADSYN1 versus DHCR7 in HNSC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NADSYN1→partner) and Y-score (partner→NADSYN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DHCR7 →	+1.089	+0.370	<.001	<.001	3	5
OV	ATP6V0E1 →	+0.688	+0.463	<.001	.002	2	6
UCEC	KLF12 →	-0.948	-0.313	.002	.001	3	5
UCEC	PJVK →	-0.603	-0.307	.002	.001	3	4
HNSC	LAMTOR1 →	+0.870	+0.592	<.001	<.001	3	4
OV	BICRAL →	-0.491	-0.351	.006	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,391 associations by consensus.

NADSYN1 vs DHCR7 — HNSC

Explore this scatter interactively →