NADSYN1

Across TCGA cell cohorts, NADSYN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,186 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NADSYN1-associated GO terms across cancer lineages are Pyridine nucleotide salvage, NAD+ biosynthetic process via the salvage pathway, and Cytosolic transport. Each is linked with NADSYN1 in more than 10 cancer types. Because this analysis shows association rather than direction, both NADSYN1-to-partner and partner-to-NADSYN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyridine nucleotide salvage grouped by NADSYN1-low versus NADSYN1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NADSYN1→partner) and Y-score (partner→NADSYN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Pyridine nucleotide salvage →	+0.206	+0.952	.008	.002	3	11
LUNG_NSCLC_LUSC	NAD+ biosynthetic process via the salvage pathway →	+0.206	+0.952	.008	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.051	+1.124	.003	.009	3	11
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid metabolic process →	+0.037	+1.115	<.001	<.001	3	11
LUNG_SCLC	Vesicle-mediated transport to the plasma membrane →	+0.044	+0.754	.001	.006	3	11
SKIN	Positive regulation of autophagy →	+0.035	+0.503	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,186 associations by consensus.

Pyridine nucleotide salvage by NADSYN1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →