NADK2

Across TCGA cell cohorts, NADK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,484 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NADK2-associated GO terms across cancer lineages are NADP+ biosynthetic process, Establishment of mitotic sister chromatid cohesion, and Protein localization to nuclear inner membrane. Each is linked with NADK2 in more than 15 cancer types. Because this analysis shows association rather than direction, both NADK2-to-partner and partner-to-NADK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NADP+ biosynthetic process grouped by NADK2-low versus NADK2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NADK2→partner) and Y-score (partner→NADK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	NADP+ biosynthetic process →	+0.253	+1.702	<.001	.001	3	16
OESOPHAGUS	Establishment of mitotic sister chromatid cohesion →	+0.102	+0.961	.007	.003	3	12
UPPER_AERODIGESTIVE_TRACT	Protein localization to nuclear inner membrane →	+0.145	+0.867	<.001	<.001	3	12
BREAST	NADP+ metabolic process →	+0.116	+0.952	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.129	+1.150	.005	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of cell cycle G2/M phase transition →	+0.067	+0.899	.004	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,484 associations by consensus.

NADP+ biosynthetic process by NADK2 expression — LIVER

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