NACC2

Across TCGA patient cohorts, NACC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,540 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NACC2-associated proteins across cancer lineages are SH3GLB2, MAP1A, and NT5E. Each is linked with NACC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both NACC2-to-partner and partner-to-NACC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NACC2 versus SH3GLB2 in GBM, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NACC2→partner) and Y-score (partner→NACC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SH3GLB2 →	+0.346	+0.496	.007	.004	3	5
UCEC	MAP1A →	+0.492	+0.522	<.001	<.001	3	5
GBM	NT5E →	+0.685	+0.561	.001	.004	3	4
GBM	UBR5 →	-0.157	-0.477	<.001	<.001	3	4
GBM	THOC2 →	-0.275	-0.513	<.001	<.001	3	4
UCEC	TPPP3 →	+0.914	+0.451	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,540 associations by consensus.

NACC2 vs SH3GLB2 — GBM

Explore this scatter interactively →