NACC1

Across TCGA patient cohorts, NACC1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,945 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NACC1-associated genes across cancer lineages are ZNF443, ZNF823, and ZNF627. Each is linked with NACC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NACC1-to-partner and partner-to-NACC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NACC1 versus ZNF443 in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NACC1→partner) and Y-score (partner→NACC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZNF443 →	+0.874	+0.373	<.001	.001	3	6
HNSC	ZNF823 →	+0.683	+0.187	<.001	.001	3	6
HNSC	ZNF627 →	+0.672	+0.205	<.001	.001	3	6
CCRCC	EGFL7 →	-1.077	-0.152	<.001	.002	3	6
UCEC	TRMT1 →	+1.009	+0.263	<.001	<.001	2	6
LSCC	C19orf44 →	+0.612	+0.288	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,945 associations by consensus.

NACC1 vs ZNF443 — OV

Explore this scatter interactively →