NACAP2

Across TCGA pan-cancer cohorts, NACAP2 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated NACAP2 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher NACAP2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NACAP2 expression acts as an unfavorable survival marker, although some lineages such as CESC and BLCA show a favorable association.

MESO, SKCM, and CESC are the cancer types where NACAP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Quartile	All	0.212	0.426	.001	38	view →
SKCM	DFS	Median	II,III,IV	0.457	0.660	.002	22	view →
CESC	OS	Median	II,III,IV	0.650	0.442	.018	12	view →
UCEC	OS	Quartile	II,III,IV	0.773	0.904	.024	10	view →
BLCA	OS	Tertile	II,III,IV	0.687	0.570	.028	10	view →
STAD	DFS	Median	II,III,IV	0.458	0.642	.011	7	view →
COAD	OS	Median	All	0.529	0.770	.027	6	view →
THCA	OS	Median	III,IV	1.000	0.587	.033	5	view →
LUAD	DFS	Median	II,III,IV	0.367	0.180	.041	4	view →
BRCA	DFS	Median	III,IV	0.611	0.401	.035	4	view →
READ	OS	Tertile	IV	0.617	1.000	.024	3	view →
GBM	DFS	Median	All	0.363	0.217	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

NACAP2–MESO (OS)

Open the MESO breakdown →