Across TCGA patient cohorts, NACA4P mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NACA4P-associated genes across cancer lineages are PKC-a_pS657, Rab11, and Rb. Each is linked with NACA4P in more than 1 cancer types. Because this analysis shows association rather than direction, both NACA4P-to-partner and partner-to-NACA4P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NACA4P→partner) and Y-score (partner→NACA4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PKC-a_pS657 →	+0.756	+3.009	<.001	.019	3	1
UCEC	Rab11 →	-0.162	-3.169	.042	.020	3	1
UCEC	Rb →	-0.231	-3.156	.018	.020	2	1
UCEC	Bid →	-0.154	-3.169	.019	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

NACA4P survival (RNA) · tumor vs normal (RNA) · all NACA4P data types