NACA3P

Across TCGA pan-cancer cohorts, NACA3P RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated NACA3P data layer compared with 2 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher NACA3P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NACA3P expression acts as an unfavorable survival marker, although some lineages such as UCEC and READ show a favorable association.

LIHC, UVM, and UCEC are the cancer types where NACA3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Tertile	All	0.452	0.643	<.001	75	view →
UVM	DFS	Median	III,IV	0.458	0.828	.005	45	view →
UCEC	DFS	Tertile	All	0.822	0.575	.009	32	view →
ACC	OS	Median	All	0.702	0.886	.005	29	view →
KIRP	OS	Median	II,III,IV	0.730	0.907	.007	26	view →
READ	DFS	Median	All	0.776	0.264	.001	24	view →
SKCM	DFS	Tertile	All	0.687	0.778	.002	22	view →
LAML	DFS	Median	All	0.531	0.246	.024	20	view →
MESO	DFS	Median	III,IV	0.651	0.248	.012	18	view →
STAD	DFS	Median	III,IV	0.515	0.656	.018	16	view →
CHOL	OS	Median	All	0.365	0.856	.004	11	view →
THCA	DFS	Median	All	0.870	0.780	.013	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

NACA3P–LIHC (DFS)

Open the LIHC breakdown →