NACA3P

Across TCGA pan-cancer cohorts, NACA3P mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NACA3P data layer compared with 19 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher NACA3P mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NACA3P expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

LSCC and HNSC are the cancer types where NACA3P mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	0.389	1.000	.020	12	view →
HNSC	DFS	Median	All	0.877	0.588	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NACA3P–LSCC (DFS)

Open the LSCC breakdown →