NACA2

Across TCGA patient cohorts, NACA2 protein abundance is significantly associated with the RNA expression of many other genes, with 307 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible NACA2-associated genes across cancer lineages are PITX3, ANGEL1, and CHRNB3. Each is linked with NACA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NACA2-to-partner and partner-to-NACA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NACA2 versus PITX3 in PDAC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NACA2→partner) and Y-score (partner→NACA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PITX3 →	+0.151	+0.415	.008	.005	3	1
PDAC	ANGEL1 →	+0.434	+0.571	<.001	.008	3	1
PDAC	CHRNB3 →	+0.315	+0.579	.002	.007	3	1
PDAC	GPR37 →	+0.678	+0.428	<.001	.001	3	1
PDAC	P2RY6 →	+0.571	+0.525	.001	.002	3	1
PDAC	ASPHD1 →	-1.303	-0.573	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 307 associations by consensus.

NACA2 vs PITX3 — PDAC

Explore this scatter interactively →