NACA2

Across TCGA cell cohorts, NACA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,751 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NACA2-associated GO terms across cancer lineages are Transcription pausing by RNA polymerase II, P-body assembly, and Neutrophil-mediated killing of fungus. Each is linked with NACA2 in more than 10 cancer types. Because this analysis shows association rather than direction, both NACA2-to-partner and partner-to-NACA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription pausing by RNA polymerase II grouped by NACA2-low versus NACA2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NACA2→partner) and Y-score (partner→NACA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription pausing by RNA polymerase II →	+0.145	+0.613	<.001	<.001	3	11
OVARY	P-body assembly →	+0.069	+0.253	<.001	.001	3	10
URINARY_TRACT	Neutrophil-mediated killing of fungus →	+0.205	+0.491	<.001	<.001	2	10
BONE	Metaphase/anaphase transition of cell cycle →	+0.254	+0.969	<.001	<.001	3	9
BREAST	Metanephric proximal tubule development →	+0.212	+0.452	<.001	<.001	3	8
BONE	Response to dehydroepiandrosterone →	+0.219	+0.880	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,751 associations by consensus.

Transcription pausing by RNA polymerase II by NACA2 expression — BONE

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