NABP2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NABP2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NABP2 data layer compared with 28 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NABP2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NABP2 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LSCC show a favorable association.

CCRCC, LUAD, and HNSC are the cancer types where NABP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCDFSQuartileAll0.5280.917.00241view →
LUADOSMedianII,III,IV0.3440.776.0264view →
HNSCOSTertileAll0.7770.925.0213view →
PDACDFSMedianIV0.9820.234.0493view →
LSCCDFSMedianAll0.9790.903.0362view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NABP2–CCRCC (DFS)

Kaplan–Meier survival curve for NABP2 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration