NABP2

Across TCGA patient cohorts, NABP2 mutation is significantly associated with the RNA expression of many other genes, with 510 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NABP2-associated genes across cancer lineages are RNU6-794P, BTBD10, and PRSS53. Each is linked with NABP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NABP2-to-partner and partner-to-NABP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-794P grouped by NABP2-low versus NABP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NABP2→partner) and Y-score (partner→NABP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-794P →	+0.241	+3.716	<.001	.002	3	2
UCEC	BTBD10 →	+0.554	+3.475	.005	.002	3	1
UCEC	PRSS53 →	+0.293	+3.254	.006	.008	3	1
UCEC	VPS26B →	+0.484	+3.606	.004	.001	3	1
UCEC	NCAPD3 →	+0.907	+3.595	<.001	.001	3	1
UCEC	BUB3 →	+0.541	+3.584	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 510 associations by consensus.

RNU6-794P by NABP2 expression — UCEC

Explore this box plot interactively →