NABP2

Across TCGA patient cohorts, NABP2 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NABP2-associated genes across cancer lineages are INPP4B, JNK2, and MEK1. Each is linked with NABP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NABP2-to-partner and partner-to-NABP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by NABP2-low versus NABP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NABP2→partner) and Y-score (partner→NABP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.416	-3.000	.010	.036	3	1
UCEC	JNK2 →	+0.323	+3.459	.001	.005	3	1
UCEC	MEK1 →	+0.389	+3.000	.034	.036	3	1
UCEC	Myosin-IIa_pS1943 →	+0.243	+2.335	.019	.020	3	1
UCEC	PCNA →	+0.225	+2.321	.038	.035	3	1
UCEC	Rab25 →	-0.647	-3.169	<.001	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

INPP4B by NABP2 expression — UCEC

Explore this box plot interactively →