NABP2

Across TCGA cell cohorts, NABP2 mutation is significantly associated with the mutation status of many other genes, with 1,787 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NABP2-associated genes across cancer lineages are DERA, SLC25A37, and ADAM33. Each is linked with NABP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NABP2-to-partner and partner-to-NABP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DERA grouped by NABP2-low versus NABP2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NABP2→partner) and Y-score (partner→NABP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DERA →	+3.584	+3.007	.008	.008	1	2
LARGE_INTESTINE	SLC25A37 →	+3.000	+3.000	.003	.003	1	2
LARGE_INTESTINE	ADAM33 →	+3.000	+3.369	<.001	<.001	1	2
LARGE_INTESTINE	PDE9A →	+3.321	+3.544	<.001	<.001	1	2
LARGE_INTESTINE	SMPDL3A →	+3.415	+3.215	.002	.002	1	2
LARGE_INTESTINE	RBM10 →	+2.321	+2.919	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,787 associations by consensus.

DERA by NABP2 expression — LARGE_INTESTINE

Explore this box plot interactively →