NABP1

Across TCGA pan-cancer cohorts, NABP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NABP1 data layer compared with 20 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher NABP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NABP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and OV show a favorable association.

PDAC, LSCC, and OV are the cancer types where NABP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	II,III,IV	0.253	0.959	<.001	70	view →
LSCC	DFS	Quartile	II,III,IV	1.000	0.678	.009	12	view →
OV	DFS	Median	All	1.000	0.610	.034	4	view →
HNSC	OS	Tertile	II,III,IV	1.000	0.708	.018	4	view →
LUAD	OS	Median	II,III,IV	0.224	0.764	.015	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NABP1–PDAC (DFS)

Open the PDAC breakdown →