NABP1

Across TCGA patient cohorts, NABP1 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NABP1-associated genes across cancer lineages are JNK2, mTOR, and SCD. Each is linked with NABP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NABP1-to-partner and partner-to-NABP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by NABP1-low versus NABP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NABP1→partner) and Y-score (partner→NABP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.236	+3.000	.039	.037	3	1
UCEC	mTOR →	-0.336	-3.000	<.001	.037	3	1
UCEC	SCD →	-0.134	-2.986	.036	.037	3	1
UCEC	p27_pT198 →	+0.161	+3.000	.009	.037	2	1
UCEC	Shc_pY317 →	-0.197	-3.000	.025	.037	2	1
UCEC	Claudin-7 →	-0.710	-3.000	.015	.037	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

JNK2 by NABP1 expression — UCEC

Explore this box plot interactively →