NAB2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NAB2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,501 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NAB2-associated genes across cancer lineages are PTGES3, KANSL2, and CKS1B. Each is linked with NAB2 in more than 5 cancer types. Because this analysis shows association rather than direction, both NAB2-to-partner and partner-to-NAB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAB2 versus PTGES3 in COAD, with a Pearson correlation of 0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAB2→partner) and Y-score (partner→NAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPTGES3 →+0.854+1.418.009.00136
COADKANSL2 →+0.696+1.079.001.00435
COADCKS1B →+1.562+1.634.001.00935
COADZNF140 →+0.648+1.240<.001<.00135
LSCCCCDC34 →+0.751+0.412<.001<.00135
LSCCPA2G4 →+0.518+0.457<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,501 associations by consensus.

NAB2 vs PTGES3 — COAD

Per-sample scatter of NAB2 vs PTGES3 in COAD (Pearson r = 0.88).

Explore this scatter interactively →

Exploration