NAB1

Across TCGA cell cohorts, NAB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,575 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible NAB1-associated GO terms across cancer lineages are Mitotic G2/M transition checkpoint, Centrosome duplication, and Microtubule organizing center organization. Each is linked with NAB1 in more than 11 cancer types. Because this analysis shows association rather than direction, both NAB1-to-partner and partner-to-NAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic G2/M transition checkpoint grouped by NAB1-low versus NAB1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAB1→partner) and Y-score (partner→NAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Mitotic G2/M transition checkpoint →	+0.071	+0.824	<.001	<.001	3	12
BREAST	Centrosome duplication →	+0.087	+1.712	<.001	<.001	3	12
LARGE_INTESTINE	Microtubule organizing center organization →	+0.074	+0.970	<.001	<.001	3	12
KIDNEY	Positive regulation of organelle assembly →	+0.053	+0.837	<.001	.004	3	11
LUNG_SCLC	Peptidyl-serine modification →	+0.085	+0.733	<.001	<.001	3	11
LUNG_SCLC	Mitotic spindle assembly →	+0.100	+1.029	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,575 associations by consensus.

Mitotic G2/M transition checkpoint by NAB1 expression — BLOOD_Myeloma

Explore this box plot interactively →