NAB1

Across TCGA cell cohorts, NAB1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible NAB1-associated genes across cancer lineages are OR8B12, OR1L3, and OR4F5. Each is linked with NAB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAB1-to-partner and partner-to-NAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8B12 grouped by NAB1-low versus NAB1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAB1→partner) and Y-score (partner→NAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR8B12 →	+0.017	+4.807	<.001	.003	3	1
OVARY	OR1L3 →	+0.047	+4.029	<.001	.009	3	1
OVARY	OR4F5 →	+0.012	+4.807	<.001	.003	3	1
OVARY	OR8B4 →	+0.015	+4.807	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR8B12 by NAB1 expression — OVARY

Explore this box plot interactively →