NAALADL2-AS3

Across TCGA pan-cancer cohorts, NAALADL2-AS3 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated NAALADL2-AS3 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher NAALADL2-AS3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NAALADL2-AS3 expression acts as an unfavorable survival marker.

PAAD, ACC, and READ are the cancer types where NAALADL2-AS3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Tertile	All	0.283	0.521	<.001	72	view →
ACC	OS	Tertile	All	0.113	0.822	<.001	63	view →
READ	DFS	Tertile	IV	0.069	0.645	<.001	57	view →
LUSC	OS	Tertile	III,IV	0.277	0.592	.002	42	view →
UCEC	DFS	Tertile	All	0.256	0.670	<.001	42	view →
OV	DFS	Tertile	IV	0.272	0.508	.007	24	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
PRAD	DFS	Quartile	All	0.872	0.951	<.001	18	view →
THYM	DFS	Tertile	II,III,IV	0.247	0.767	.025	12	view →
COAD	OS	Tertile	III,IV	0.588	0.797	.019	12	view →
BLCA	OS	Tertile	III,IV	0.384	0.606	.025	9	view →
SKCM	OS	Tertile	II,III,IV	0.500	0.747	.019	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

NAALADL2-AS3–PAAD (OS)

Open the PAAD breakdown →