NAALAD2

Across TCGA patient cohorts, NAALAD2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,889 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NAALAD2-associated genes across cancer lineages are TMSB15B-AS1, PTBP2, and SPINK4. Each is linked with NAALAD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAALAD2-to-partner and partner-to-NAALAD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAALAD2 versus TMSB15B-AS1 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAALAD2→partner) and Y-score (partner→NAALAD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TMSB15B-AS1 →	+0.952	+1.710	.004	.004	3	2
PDAC	PTBP2 →	-0.437	-0.571	.008	.001	3	1
PDAC	SPINK4 →	+3.530	+0.737	.003	.006	3	1
PDAC	DSC2 →	-1.075	-0.814	.001	.002	3	1
PDAC	DMRTC2 →	+0.026	+0.574	<.001	.002	3	1
PDAC	MINDY1 →	-0.422	-0.717	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,889 associations by consensus.

NAALAD2 vs TMSB15B-AS1 — UCEC

Explore this scatter interactively →