NAALAD2

Across TCGA cell cohorts, NAALAD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,847 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NAALAD2-associated GO terms across cancer lineages are RNA catabolic process, Heterochromatin formation, and Regulation of mRNA catabolic process. Each is linked with NAALAD2 in more than 13 cancer types. Because this analysis shows association rather than direction, both NAALAD2-to-partner and partner-to-NAALAD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA catabolic process grouped by NAALAD2-low versus NAALAD2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAALAD2→partner) and Y-score (partner→NAALAD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RNA catabolic process →	+0.088	+1.826	<.001	<.001	3	14
BONE	Heterochromatin formation →	+0.085	+1.415	.003	.005	3	12
BONE	Regulation of mRNA catabolic process →	+0.039	+1.187	.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA processing →	+0.090	+0.599	.001	.002	3	12
UPPER_AERODIGESTIVE_TRACT	Heterochromatin organization →	+0.047	+0.434	.001	.009	3	12
BONE	Nucleic acid catabolic process →	+0.066	+1.569	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,847 associations by consensus.

RNA catabolic process by NAALAD2 expression — BONE

Explore this box plot interactively →