NAAA

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NAAA protein abundance is significantly associated with the RNA expression of many other genes, with 13,504 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NAAA-associated genes across cancer lineages are GZMK, CD2, and CD48. Each is linked with NAAA in more than 6 cancer types. Because this analysis shows association rather than direction, both NAAA-to-partner and partner-to-NAAA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAAA versus GZMK in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAAA→partner) and Y-score (partner→NAAA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVGZMK →+1.226+0.471<.001.00137
OVCD2 →+1.624+0.527<.001<.00137
OVCD48 →+1.094+0.449.002.00237
GBMCCR2 →+1.136+0.669<.001<.00137
OVNCKAP1L →+1.107+0.460.003.00337
HNSCWDFY4 →+0.911+0.464<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,504 associations by consensus.

NAAA vs GZMK — OV

Per-sample scatter of NAAA vs GZMK in OV (Pearson r = 0.40).

Explore this scatter interactively →

Exploration