NAA60

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NAA60 mutation is significantly associated with the RNA expression of many other genes, with 1,733 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA60-associated genes across cancer lineages are LINC02690, RN7SL402P, and ATP5MGP6. Each is linked with NAA60 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAA60-to-partner and partner-to-NAA60 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02690 grouped by NAA60-low versus NAA60-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA60→partner) and Y-score (partner→NAA60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCLINC02690 →+0.229+4.200<.001.00432
SKCMRN7SL402P →+0.365+4.913<.001.00232
SKCMATP5MGP6 →+0.496+4.595<.001.00432
CESCRPL6P29 →+0.061+3.855.006.00831
CESCLINC02151 →+0.061+4.595<.001.00131
CESCLINC02559 →+0.871+5.927<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,733 associations by consensus.

LINC02690 by NAA60 expression — CESC

Box plot of LINC02690 in NAA60-low vs NAA60-high samples in CESC.

Explore this box plot interactively →

Exploration