NAA40

Across TCGA pan-cancer cohorts, NAA40 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NAA40 data layer compared with 28 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NAA40 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NAA40 expression acts as an unfavorable survival marker.

COAD, BLCA, and UVM are the cancer types where NAA40 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.144	0.801	.001	30	view →
BLCA	OS	Median	III,IV	0.051	0.684	<.001	24	view →
UVM	OS	Median	All	0.292	0.674	.035	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	DFS	Median	III,IV	0.088	0.613	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NAA40–COAD (OS)

Open the COAD breakdown →