NAA25

Across TCGA patient cohorts, NAA25 mutation is significantly associated with the RNA expression of many other genes, with 2,683 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA25-associated genes across cancer lineages are RPL22P14, ARPP19P2, and TRAJ21. Each is linked with NAA25 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAA25-to-partner and partner-to-NAA25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL22P14 grouped by NAA25-low versus NAA25-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA25→partner) and Y-score (partner→NAA25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL22P14 →	+0.163	+3.496	<.001	.008	3	3
READ	ARPP19P2 →	+0.373	+4.533	<.001	.004	3	2
READ	TRAJ21 →	+0.907	+4.421	<.001	.009	3	2
LIHC	DUTP8 →	+0.124	+5.647	<.001	.004	3	2
CESC	HTT-AS →	+0.280	+3.934	<.001	.003	3	2
SKCM	ATP1B2 →	-1.492	-2.800	.009	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,683 associations by consensus.

RPL22P14 by NAA25 expression — COAD

Explore this box plot interactively →