NAA25

Across TCGA patient cohorts, NAA25 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA25-associated genes across cancer lineages are GAPDH, 14-3-3_beta, and Cyclin-B1. Each is linked with NAA25 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAA25-to-partner and partner-to-NAA25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by NAA25-low versus NAA25-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA25→partner) and Y-score (partner→NAA25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.376	+1.125	.020	.033	3	3
UCEC	14-3-3_beta →	-0.090	-2.475	.002	.001	3	2
UCEC	Cyclin-B1 →	+0.498	+2.169	.003	.003	3	2
STAD	EGFR →	+0.420	+3.000	<.001	.034	3	1
UCEC	eEF2 →	+0.290	+1.765	.007	.011	3	1
UCEC	EGFR_pY1068 →	-0.190	-1.502	.012	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

GAPDH by NAA25 expression — UCEC

Explore this box plot interactively →