NAA25

Across TCGA cell cohorts, NAA25 mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NAA25-associated genes across cancer lineages are Quizartinib, 150412, and Sinularin. Each is linked with NAA25 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAA25-to-partner and partner-to-NAA25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Quizartinib grouped by NAA25-low versus NAA25-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA25→partner) and Y-score (partner→NAA25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Quizartinib →	+0.428	+2.652	.007	.045	3	1
LARGE_INTESTINE	150412 →	+0.440	+2.777	.008	.038	2	1
LARGE_INTESTINE	Sinularin →	+0.442	+2.777	.004	.038	2	1
LARGE_INTESTINE	Nutlin-3a (-) →	+0.727	+2.646	.048	.047	1	1
LARGE_INTESTINE	PFI3 →	+0.263	+2.646	.024	.047	1	1
LARGE_INTESTINE	PCI-34051 →	+0.460	+2.646	.016	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Quizartinib by NAA25 expression — LARGE_INTESTINE

Explore this box plot interactively →