NAA20

Across TCGA pan-cancer cohorts, NAA20 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated NAA20 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher NAA20 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NAA20 expression acts as an unfavorable survival marker, although some lineages such as LSCC and UCEC show a favorable association.

LSCC, LUAD, and CCRCC are the cancer types where NAA20 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	II,III,IV	0.912	0.442	<.001	69	view →
LUAD	DFS	Quartile	All	0.429	1.000	.010	13	view →
CCRCC	OS	Quartile	II,III,IV	0.374	0.828	.003	12	view →
GBM	DFS	Tertile	All	0.236	0.476	<.001	10	view →
PDAC	OS	Median	All	0.799	0.881	.021	10	view →
UCEC	DFS	Median	III,IV	0.905	0.444	.031	8	view →
HNSC	OS	Median	II,III,IV	1.000	0.953	.019	6	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

NAA20–LSCC (DFS)

Open the LSCC breakdown →