NAA20

Across TCGA patient cohorts, NAA20 mutation is significantly associated with the RNA expression of many other genes, with 269 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA20-associated genes across cancer lineages are SNRPGP17, CCL5, and PRAG1. Each is linked with NAA20 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAA20-to-partner and partner-to-NAA20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPGP17 grouped by NAA20-low versus NAA20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA20→partner) and Y-score (partner→NAA20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNRPGP17 →	+0.248	+1.879	.003	.009	3	1
UCEC	CCL5 →	+1.369	+3.928	<.001	<.001	3	1
UCEC	PRAG1 →	+0.687	+3.491	.009	.002	3	1
UCEC	PCDHGB9P →	+0.295	+3.491	.003	.002	3	1
UCEC	TRAC →	+1.301	+2.818	<.001	.001	3	1
COAD	PRSS40B →	+0.014	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 269 associations by consensus.

SNRPGP17 by NAA20 expression — UCEC

Explore this box plot interactively →