NAA20

Across TCGA patient cohorts, NAA20 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA20-associated genes across cancer lineages are Caspase-7-cleavedD198, C-Raf, and p27_pT198. Each is linked with NAA20 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAA20-to-partner and partner-to-NAA20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by NAA20-low versus NAA20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA20→partner) and Y-score (partner→NAA20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.801	+3.321	.009	.010	3	1
UCEC	C-Raf →	+0.156	+3.000	.037	.036	3	1
UCEC	p27_pT198 →	+0.123	+3.321	.027	.010	1	1
UCEC	p62 Lck ligand →	+0.398	+3.321	.019	.010	1	1
UCEC	4E-BP1 →	+0.519	+3.321	<.001	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Caspase-7-cleavedD198 by NAA20 expression — UCEC

Explore this box plot interactively →