NAA20

Across TCGA cell cohorts, NAA20 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,221 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NAA20-associated GO terms across cancer lineages are Negative regulation of appetite by leptin-mediated signaling pathway, Regulation of peroxisome organization, and miRNA metabolic process. Each is linked with NAA20 in more than 6 cancer types. Because this analysis shows association rather than direction, both NAA20-to-partner and partner-to-NAA20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of appetite by leptin-mediated signaling pathway grouped by NAA20-low versus NAA20-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA20→partner) and Y-score (partner→NAA20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of appetite by leptin-mediated signaling pathway →	+0.132	+0.901	<.001	<.001	2	7
PANCREAS	Regulation of peroxisome organization →	+0.156	+0.675	.002	.005	3	6
UPPER_AERODIGESTIVE_TRACT	miRNA metabolic process →	-0.088	-0.477	.001	.003	3	6
SKIN	Negative regulation of purine nucleotide metabolic process →	-0.091	-0.507	<.001	.005	2	7
LUNG_NSCLC_LUSC	Positive regulation of protein transport →	-0.062	-0.885	.001	.005	3	6
PANCREAS	Regulation of macroautophagy →	-0.042	-0.722	.004	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,221 associations by consensus.

Negative regulation of appetite by leptin-mediated signaling pathway by NAA20 expression — BREAST

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