NAA15

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NAA15 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NAA15 data layer compared with 28 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NAA15 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated NAA15 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, READ, and SCLC are the cancer types where NAA15 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSMedianII,III,IV0.9280.302.00924view →
READOSMedianAll0.1980.829.00118view →
SCLCOSMedianAll0.3010.711.01812view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

NAA15–UCEC (DFS)

Kaplan–Meier survival curve for NAA15 mutant vs wild-type samples in UCEC.

Open the UCEC breakdown →

Exploration