NAA15

Across TCGA pan-cancer cohorts, NAA15 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated NAA15 data layer compared with 28 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NAA15 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NAA15 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, PDAC, and LUAD are the cancer types where NAA15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	1.000	0.466	.009	40	view →
PDAC	OS	Median	IV	0.381	0.951	.006	39	view →
LUAD	OS	Quartile	All	0.527	1.000	.001	29	view →
CCRCC	OS	Quartile	All	0.677	0.925	.001	20	view →
LSCC	DFS	Median	II,III,IV	1.000	0.842	.007	14	view →
HNSC	OS	Quartile	II,III,IV	1.000	0.885	.007	13	view →
GBM	DFS	Tertile	All	0.664	0.798	.009	11	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

NAA15–UCEC (DFS)

Open the UCEC breakdown →