NAA15

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NAA15 mutation is significantly associated with the RNA expression of many other genes, with 5,521 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA15-associated genes across cancer lineages are TRAJ28, FCGR1A, and PATL1. Each is linked with NAA15 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAA15-to-partner and partner-to-NAA15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ28 grouped by NAA15-low versus NAA15-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA15→partner) and Y-score (partner→NAA15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCATRAJ28 →+0.504+3.756.001.00133
UCECFCGR1A →+0.420+1.705.002.00533
UCECPATL1 →+0.496+3.069<.001<.00133
UCECPDCD1 →+0.767+2.202<.001<.00133
UCECHLA-DQA1 →+0.706+1.684.002.00633
UCECTXN2P1 →+0.227+1.447<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,521 associations by consensus.

TRAJ28 by NAA15 expression — BLCA

Box plot of TRAJ28 in NAA15-low vs NAA15-high samples in BLCA.

Explore this box plot interactively →

Exploration