NAA15

Across TCGA patient cohorts, NAA15 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA15-associated genes across cancer lineages are ASNS, 14-3-3_epsilon, and eIF4E. Each is linked with NAA15 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAA15-to-partner and partner-to-NAA15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by NAA15-low versus NAA15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA15→partner) and Y-score (partner→NAA15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.365	+1.662	<.001	.010	3	3
CESC	14-3-3_epsilon →	+0.098	+3.169	.024	.017	3	2
UCEC	eIF4E →	+0.216	+2.146	<.001	<.001	3	2
UCEC	PDCD4 →	-0.460	-2.502	<.001	.001	3	2
UCEC	STAT3_pY705 →	-0.361	-2.070	<.001	.001	3	2
UCEC	TIGAR →	+0.105	+1.322	.017	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

ASNS by NAA15 expression — UCEC

Explore this box plot interactively →