NAA15

Across TCGA cell cohorts, NAA15 mutation is significantly associated with the RNA expression of many other genes, with 427 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NAA15-associated genes across cancer lineages are FSHB, LCE1C, and IL17A. Each is linked with NAA15 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAA15-to-partner and partner-to-NAA15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FSHB grouped by NAA15-low versus NAA15-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA15→partner) and Y-score (partner→NAA15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	FSHB →	+0.032	+5.321	<.001	.005	3	2
BLOOD_Leukemia	LCE1C →	+0.432	+4.922	.002	.009	3	2
PANCREAS	IL17A →	+0.006	+5.614	<.001	.002	3	1
PANCREAS	SPATA3 →	+0.370	+5.614	<.001	.002	3	1
OVARY	PPY →	+0.212	+4.029	<.001	.009	3	1
STOMACH	SSX7 →	+0.433	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 427 associations by consensus.

FSHB by NAA15 expression — CNS

Explore this box plot interactively →