NAA11

Across TCGA patient cohorts, NAA11 mutation is significantly associated with the RNA expression of many other genes, with 1,318 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA11-associated genes across cancer lineages are TIMM22, PSMC3IP, and RN7SL294P. Each is linked with NAA11 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAA11-to-partner and partner-to-NAA11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIMM22 grouped by NAA11-low versus NAA11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA11→partner) and Y-score (partner→NAA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIMM22 →	+0.487	+3.960	<.001	<.001	3	3
UCEC	PSMC3IP →	+0.688	+3.345	.001	.005	3	3
LUAD	RN7SL294P →	+0.078	+5.155	<.001	.002	3	3
SKCM	DHDDS →	+0.463	+3.622	.001	.001	3	3
SKCM	TUBG1 →	+0.420	+2.748	.006	.002	3	3
SKCM	CAPZB →	+0.366	+2.417	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,318 associations by consensus.

TIMM22 by NAA11 expression — UCEC

Explore this box plot interactively →